Changes Cigarettes More Vulnerable To Cancer Lung tuberculosis

Changes Cigarettes More Vulnerable To Cancer Lung tuberculosis

Suck cigarettes today have greater risk for lung compared with some decades ago due to changes in cigarette design, so the results of a new study.

As many as half the cases of lung cancer in the U.S. may be caused by the change, said Dr. David Burns of the University of California, San Diego, the researchers at a meeting of tobacco recently.

Study found an increase in the type of lung tumor, called "adenocarcinoma" higher in the United States compared with Australia, even though both countries are switching to what's called a cigarette lighter at the same time.

"The most likely explanation is a change in the cigarette," said Burns in an interview. "Cigarettes are sold in Australia contain nitrosamine` `degree lower, which is known by the name` `carcinogen, compared with that sold in the United States."

He admitted that while the evidence is that need further research.

Study submitted for the meeting of the Research on Tobacco and nicotine, on the comparison of smoking behavior in different age groups for four decades - how much they smoke, when they start, when they stop - and how to change the risk of cancer.

The risk of squamous cell carcinoma (SCC) remains the same during that time, so the findings of Burns. However, increasing the risk of adenocarcinoma. That is 65 percent to 70 percent of cases of lung cancer is a new show in the U.S. but not more than 40 percent of lung cancer in Australia, he said.

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Pleural Mesothelioma Disease

Still about the type of cancer tuberculosis, there is one type of cancer that is not actually included in the cancer tuberculosis, but because the location is very close to the tuberculosis is usually discussed in relation to cancer tuberculosis. The doctor called Pleural Mesothelioma, the cancer to grow cells from the pleura, the thin layer envelop the lungs. Mesothelioma word comes from the mesothelium, a network of thin layers envelop most of the organs in the body. Consists of two layers, the first layer of paste on the organ is protected, while the second layer form a layer outside the first bag. Mesothelium produce liquids that fill the space between the second layer as a lubricant, to facilitate the movement of organs such as the movement dilapisinya heart pumping blood, and mengecilnya inflate the lungs take in air and release it again. Place is based, have Mesothelium name a few. Peritoneum is a network of mesothelial conceal most of the organs in the stomach cavity. Pleura is the network that separates the network Mesothelial lungs with the chest wall cavity. Pleura layer attached on tuberculosis called Visceral pleura, while diluarnya layer called the Parietal pleura. Pericardium conceal and protect the heart. Network mesothelial reproductive tool that wrapped up the men called in Tunica vaginalis testis, while the woman called Tunica serosa uteri.
Cells in the mesothelium mutation then split themselves are not harmful to the surrounding network called cancer Mesothelium or Mesothelioma. Most cases of mesothelioma begin Pleura and Peritoneum. Mesothelioma of the Pleura called developed Pleural Mesithelioma. Because of Pleural Mesothelioma is a cancer cell is derived from cells Mesothelium, it is not classified as a type of cancer cells tuberculosis. But because the location is very bedekatan the lungs, the usual Pleural Mesothelioma also discussed in relation to cancer tuberculosis.

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Symptoms of Mesothelioma - Human Health

Symptoms of mesothelioma

The most common symptoms of cancer is of breath, chest pain, weight loss, nausea and loss of energy. Abdominal peritoneal mesothelioma symptoms include restlessness, swelling and inflammation, or stomach. Pleural Mesothelioma Symptoms include chest pain and cough, usually without phlegm.

Because many symptoms of the disease, patients are often not diagnosed. Most doctors have little or no experience with mesothelioma, the patient often through a series of tests and referrals to doctors with the accurate diagnosis is reached. Characteristics that are less than the type of cancer that the doctor is the first symptom - a little non-specific - a small complaint, it is not serious asbestos-related cancer. In fact, often more than six months between first symptoms and diagnosis of mesothelioma.

Dysphagia - difficulty swallowing - is also a symptom of pleural mesothelioma, but usually in the stadium. Unlike lung cancer or throat, it is very rare for patients with mesothelioma have been spitting blood or swelling in the lymph nodes.

Society, with two models showing symptoms of peritoneal mesothelioma, the demand for medical services: (1) abdominal pain, often localized and associated with the dominant tumor mass with little or no ascites, or (2), without abdominal pain, l 'but with ascites extension and stomach.

If a patient has no symptoms, can not complain, the doctor and the doctor can not provide a detailed analysis, the detection of cancer. This is one reason, mesothelioma is very difficult - but often not diagnosed years.

Other typical symptoms of cancer in advanced stage of mesothelioma in the loss of precious time.

Malignant mesothelioma is almost exclusively on people who have been in contact with the environment and the symptoms of asbestos began in May occur decades after exposure. Doctors suspect that mesothelioma, a history of life, with special attention to exposure to asbestos and asbestos in the past, doctors have to understand that history.

Given the low incidence of cancer, most doctors have little experience, and often refer patients to specialized centers. Mesothelioma Help can help you find experts and cancer centers, and can help you, a new clinical Therapies.


Translation In French


Les symptômes du mésothéliome

Les symptômes les plus communs du cancer de souffle, douleur thoracique, perte de poids, nausées et perte d'énergie. Abdominal mésothéliome péritonéal symptômes incluent l'agitation, de l'enflure et l'inflammation, ou l'estomac. Pleural Mesothelioma Les symptômes comprennent des douleurs à la poitrine et de toux, généralement sans flegme.

Parce que de nombreux symptômes de la maladie, les patients ne sont souvent pas diagnostiquées. La plupart des médecins ont peu ou pas d'expérience avec le mésothéliome, le patient souvent par le biais d'une série de tests et de références à des médecins avec le diagnostic précis est atteint. Caractéristiques qui sont de moins que le type de cancer que le médecin est le premier symptôme - un peu non spécifique - une petite plainte, ce n'est pas grave de cancer liés à l'amiante. En effet, souvent plus de six mois entre les premiers symptômes et le diagnostic de mésothéliome.

Dysphagie - difficulté à avaler - est également un symptôme de mésothéliome pleural, mais généralement dans le stade. Contrairement au cancer du poumon ou de la gorge, il est très rare chez les patients atteints de mésothéliome ont été crachats de sang ou de gonflement des ganglions lymphatiques.

Société, avec deux modèles présentant des symptômes de mésothéliome péritonéal, la demande de services médicaux: (1) douleurs abdominales, souvent localisées et associées à la masse tumorale dominante avec peu ou pas d'ascite, ou (2), sans douleurs abdominales, de l ', mais extension de l'ascite et de l'estomac.

Si un patient n'a pas de symptômes, ne peut pas se plaindre, le médecin et le médecin ne peut pas fournir une analyse détaillée, la détection du cancer. C'est une des raisons, le mésothéliome est très difficile - mais souvent pas diagnostiqué ans.

D'autres symptômes typiques d'un cancer en stade avancé de mésothéliome dans la perte de temps précieux.

Mésothéliome malin est presque exclusivement sur les personnes qui ont été en contact avec l'environnement et les symptômes de l'amiante a commencé en Mai se décennies après l'exposition. Les médecins soupçonnent que le mésothéliome, une histoire de vie, avec une attention particulière à l'exposition à l'amiante et de l'amiante dans le passé, les médecins doivent comprendre que l'histoire.

Compte tenu de la faible incidence de cancer, la plupart des médecins ont peu d'expérience, et se réfèrent souvent les patients à des centres spécialisés. Mesothelioma Aide peuvent vous aider à trouver des experts et des centres de cancer, et peut vous aider, une nouvelle clinique des thérapies.

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Pleural Mesothelioma - Human Health

Pleural mesothelioma

Medical experts were unable to make the prognosis of pleural mesothelioma in part because relatively few cases, and it is so difficult to diagnose patients who are not members of the treatment over a longer period after the disease strikes. Studies in patients with pleural mesothelioma, which are important prognostic factors include stage of cancer, age and histology. The surgery improves the lives of patients but does not cure the disease. For patients undergoing surgery, factors associated with improved long-term survival of epithelial histology, negative lymph nodes and negative operating margins. Nodal status is an important prognostic factor. Studies have shown a median survival of patients with malignant pleural disease is 16 months.

Pleural and peritoneal fluid are buried, where two thirds of patients. Haemothorax - a collection of blood in the pleural cavity - is also a symptom. For a diagnosis, doctors use imaging techniques and histological examination and testing of molecular biology. A pleural smear examines a sample of pleural fluid under the microscope for the detection of disturbances in the organs. The test is carried out if infection of the pleural space, or if you think that the presence of an abnormal collection of pleural fluid was confirmed by X-ray of the chest. Sometimes, the tumor grows through the membrane, the source is difficult to assess.
Treatment options for pleural mesothelioma

Extrapleural pneumonectomy is a surgical procedure to a lung disease that is part of the pericardium (membrane of the heart), diaphragm (muscle between the lungs and abdomen) and the parietal pleura (membrane lining of the chest). Extrapleural pneumonectomy can improve survival, but their influence on the long term is unknown. Aggressive treatment to help some people, but it is unclear whether the survival time significantly by different treatments or combinations of functions.

Pleurectomy and decortication (removal of all or part of the outside of the lung or mesothelium), the loss of relief of symptoms, discomfort and pain caused by invasive tumors. There is always the risk of the operation, and statistics show that mortality of pleurectomy / decortication is <2%, while mortality from extrapleural pneumonectomy has between 6% and 30%.

Radiotherapy and chemotherapy is usually done after surgery, but are not effective in improving survival. Radiotherapy has been shown that pain is a term of more patients, even when control of symptoms is short.

As a single agent and combination chemotherapy have been combined and studies. Combination chemotherapy reported the highest response rate of small phase II trials, but reported toxic effects, and it is more than a combination of systems to prolong survival or symptom control, but as a regiment. Recurrent pleural effusion can be treated with pleural sclerosing procedures, but the price of failure is often compared to the tumor, so that pleural adhesion due to inability to completely expand the lungs.
The prognosis for people suffering from pleural mesothelioma

Age and morphology (epithelial, sarcomatoid or biphasic) are the main factors. Scientists have tried to be more precise (haematological parameters and histology) in the progression of the disease, and studies have shown Nova biomarkers for pleural mesothelioma, but not effective in clinical application. Advanced Imaging (PET-CT) can be used in medical diagnosis and helps to predict. Oncologists generally use the Cancer and Leukemia Group B and the European Organization for Research and Treatment of Cancer scoring system to predict the outcome.

Translation In French


Mésothéliome pleural

Les experts médicaux ont été incapables de faire le pronostic du mésothéliome pleural en partie parce que relativement peu de cas, et il est si difficile à diagnostiquer les patients qui ne sont pas membres du traitement sur une plus longue période après que la maladie frappe. Les études chez des patients atteints de mésothéliome pleural, qui sont d'importants facteurs pronostiques comprennent stade du cancer, l'âge et de l'histologie. La chirurgie améliore la vie des patients, mais ne guérit pas la maladie. Pour les patients de subir une intervention chirurgicale, les facteurs associés à l'amélioration de la survie à long terme de l'épithélium histologie, négatifs des ganglions lymphatiques et les marges d'exploitation négatif. Statut ganglionnaire est un facteur pronostique important. Des études ont montré une survie médiane des patients atteints de la maladie pleural malin est de 16 mois.

Pleural péritonéale et fluide sont enterrés, où deux tiers des patients. Haemothorax - une collecte de sang dans la cavité pleurale - est aussi un symptôme. Pour un diagnostic, les médecins utilisent des techniques d'imagerie et de l'examen histologique et les tests de biologie moléculaire. Un frottis de la plèvre examine un échantillon de liquide pleural dans le cadre du microscope pour la détection des perturbations dans les organes. L'essai est réalisé si l'infection de l'espace pleural, ou si vous pensez que la présence d'une anomalie de collecte de liquide pleural a été confirmé par la radiographie de la poitrine. Parfois, la tumeur se développe à travers la membrane, la source est difficile à évaluer.
Options de traitement pour le mésothéliome pleural

Extrapleural pneumonectomie est une procédure chirurgicale à une maladie des poumons qui fait partie du péricarde (membrane du cœur), le diaphragme (muscle entre les poumons et l'abdomen) et de la plèvre pariétale (membrane muqueuse de la poitrine). Extrapleural pneumonectomie peut améliorer la survie, mais leur influence sur le long terme est inconnue. Traitement agressif pour aider certaines personnes, mais il est difficile de savoir si le temps de survie de façon significative par les différents traitements ou combinaisons de fonctions.

Pleurectomy et le décorticage (ablation de tout ou partie de l'extérieur du poumon ou mésothélium), la perte de soulagement des symptômes, de l'inconfort et la douleur causée par les tumeurs invasives. Il ya toujours le risque de l'opération, et les statistiques montrent que la mortalité des pleurectomy / décorticage est <2%, tandis que la mortalité due à la extrapleural pneumonectomie a entre 6% et 30%.

La radiothérapie et la chimiothérapie est habituellement fait après la chirurgie, mais ne sont pas efficaces dans l'amélioration de la survie. La radiothérapie a été montré que la douleur est un terme de plus de patients, même lorsque le contrôle des symptômes est court.

Comme un seul agent et une combinaison de chimiothérapie ont été combinés et d'études. Combinaison de chimiothérapie déclaré le plus grand taux de réponse des petits essais de phase II, mais a signalé les effets toxiques, et il est plus que d'une combinaison de systèmes de prolonger la survie ou le contrôle des symptômes, mais comme un régiment. Recurrent épanchement pleural peut être traitée avec pleural sclérosante procédures, mais le prix de l'échec est souvent comparé à la tumeur, de sorte que l'adhérence pleurale due à l'impossibilité d'étendre complètement les poumons.
Le pronostic pour les personnes atteintes de mésothéliome pleural

Age et de la morphologie (épithéliales, sarcomatoid ou biphasique) sont les principaux facteurs. Les scientifiques ont essayé d'être plus précis (les paramètres hématologiques et de l'histologie) dans la progression de la maladie, et des études ont montré Nova biomarqueurs pour le mésothéliome pleural, mais pas efficaces dans l'application clinique. Advanced Imaging (PET-CT) peuvent être utilisés dans le diagnostic médical et les aide à prévoir. Oncologists généralement l'utilisation de la leucémie et le cancer du groupe B et l'Organisation européenne pour la recherche et le traitement du cancer du système de prédire l'issue.

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Mesothelioma Chemotherapy

Mesothelioma treatment chemicals for cancer chemotherapy to death, also known as malignant mesothelioma. Although many treatment options of mesothelioma has not been successful in fighting the disease. Mesothelioma, May chemotherapy were divided into two categories, traditional and new mesothelioma treatment mesothelioma.

Chemotherapy used to treat cancer in the early 1940s, scientific knowledge and understanding about the nature of the disease have the right to continue research and development of new chemotherapeutic agents specifically. Chemotherapy is most effective when a relatively "young" of cancer cells that have not been established tumor mass is very difficult to penetrate chemotherapy drugs in a solid tumor mass.

There are many drugs used to treat mesothelioma cancer chemotherapy is rare, but can not guarantee that effective treatment of malignant mesothelioma. Standard chemotherapy, most chemotherapy drugs affect the work of mesothelioma cell division or programmed cell death (apoptosis). For example, anti-angiogenic chemotherapy mesothelioma resources prevents the formation of new blood vessels (angiogenesis), preventing Tumors of oxygen and nutrients needed for Metastasis (the spread and development of the tumor).

One of the more conventional chemotherapy drugs used to treat malignant mesothelioma cisplatin. Cisplatin is a platinum, depending on the type of drug is part of a family of three drugs (including carboplatin and oxaliplatin). Cisplatin DNA cross-link agents with a variety of ways to prevent the cells quickly removed from the replication of DNA, some cell division. Today, cisplatin is often used in combination with new types of products, such as chemotherapy Alimta (pemetrexed) Onconase (ranpirnase) and / or Veglin.

Type of chemotherapy in mesothelioma

Mesothelioma chemotherapy is not always used with curative intent. Some of the most common form of mesothelioma treatment, are:

* Chemotherapy combined: mesothelioma, chemotherapy is often used in conjunction with other forms of treatment such as surgery or radiotherapy. For example trimodality treatment involves the use of radio-therapy, surgery and chemotherapy.
* Radiasi intensity modulated (IMRT)
* Neoadjuvant chemotherapy: If one member is appointed by preoperative chemotherapy, neoadjuvant chemotherapy is used to measure tumor before surgery.
* Pembantu chemotherapy: If appointed after chemotherapy, adjuvant chemotherapy after surgery, when there is a risk of cancer recurrence.
* YG alleviate chemotherapy mesothelioma chemotherapy used to treat symptoms of the disease compared with palliative care, decision-making techniques.

A low dose of chemotherapy vary according to body surface area (BSA) said that aid in determining the level of the organization. Dose with this strategy is to offer the perfect balance between chemotherapy at any time, to avoid toxic side effects.

Mesothelioma chemotherapy - effects

Chemotherapy and mesothelioma REGI exhausting physically and mentally for patients. Chemicals is to face their victims in various ways, some of which include:

* Nausea and vomiting
* Hair loss
* Reduce the number of red blood cells (anemia)
* Daily
*Constipation
* Other Tumo
* Weakened immune system
* Increased risk of cardiovascular disease
* Liver toxicity
* Nephrotoxicity
* Ototoxicity
*Cardiotoxicity

According to the patient and the severity of disease, chemotherapy can be patient and administration.

Use drugs:
*Alimta
*Anti-angiogenesis
*Cisplatine
*Onconase
*Veglin

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Symptoms of mesothelioma

Symptoms of mesothelioma

Mesothelioma symptoms, many symptoms of mesothelioma, health problems or other symptoms are not specific. Most studies mesotheliomausually symptoms begin 30-40 years after asbestos exposure akan show. Before patients with symptoms of mesothelioma, many things, many of them in terms of what is happening in my life. Exposure to asbestos, and even a few (several months) the disease broke out, a lot of time in life, to create conditions in May.
Mesothelioma in the level of other agencies. Over time, fluid accumulation and expansion of malignant tumor development. Generally, the liquid will cause the symptoms. Mesothelioma Symptoms vary depending on the tumor. Symptoms of pleural mesothelioma For pleural mesothelioma, mesothelioma, or a layer near the lungs, symptoms of breathlessness, chest pain and cough is. Unfortunately, this is also a lot of symptoms of other diseases such as pneumonia, are common. The most common symptoms of chest pain in March, but only after the advanced-stage disease. More symptoms of pleural mesothelioma in body weight is still at large. Some patients have almost no symptoms. Symptoms of peritoneal mesothelioma Abdominal peritoneal mesothelioma cancer in the hierarchy. Symptoms or abdominal swelling, weight loss, abdominal pain, in most areas. Disease, blood clots, and sometimes known to be involved in the production field. Symptoms of pericardial mesothelioma Pericardial mesothelioma, heart, pericardium, or in the film. Breast symptoms, including coughing, irregular breathing and irregular heartbeat. Other evidence of physical symptoms in the workplace - a little energy. Pericardial mesothelioma, mesothelioma is rare. Cancer, or - mesothelioma - has proved more effective treatment to halt the development.

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